The losses are the first on statewide reproductive rights ballot measures anywhere in the U.S. since the Supreme Court overturned Roe v. Wade in 2022, a ruling that struck down the nearly 50-year nationwide right to abortion, proving that abortion opponents can win on ballot measures.

Florida, Nebraska and South Dakota became the first states since Roe vs. Wade was overturned where abortion opponents prevailed on a ballot measure.

Missouri’s current law bans abortion with almost no exceptions and this amendment would allow abortion to about 24 weeks of pregnancy.