Persister cells (PCs) and cancer stem cells (CSCs), which exhibit heightened ... Emerging immunotherapies, like PD-1 and PD-L1 inhibitors, have also been linked to ferroptosis induction. PD-L1 ...

The safety and overall survival seen in the ARC-10 trial lends further support to the firm's strategy of pairing domvanalimab and zimberelimab with chemo in STAR-121.

Blocking a protein that imports lactic acid, a metabolic byproduct of cancer cells, reinvigorated exhausted T cells and led to improved tumor control in mouse models of cancer, according to a new ...

The global burden of digestive tract tumors is profound, with these cancers accounting for nearly half of all malignant ...

Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...

Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients ...

The test improved prediction of patient benefit from anti-PD-1 immune checkpoint inhibitors (ICIs) as a monotherapy and with ...

BPT958, a bifunctional PD-1 immunoconjugate with a masked IL-2 payload designed to be processed specifically in the tumor microenvironment ...

Balversa (erdafitinib) marks the first and only bladder cancer therapy to target FGFR3 alterations ... of therapy containing a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) ...

Chavez, MD, discusses the efficacy of immunotherapy for the potential treatment of extensive-stage small cell lung cancers.