Overweight and obesity are increasing globally with aging, as are life expectancy and aging‐associated disorders, including calcific aortic stenosis (AS). Studies investigating the correlation between ...

Cardiovascular health (CVH) in young adulthood is associated with CVD in later life, yet CVH in young adults in the United States falls below ideal levels, with noticeable sex differences. Research on ...

Patients with hypertrophic cardiomyopathy (HCM) are generally restricted regarding participation in competitive sports based on the potential risk of sudden cardiac death and malignant arrhythmias. As ...

In the past decade, the biological functions of various RNA modifications in mammals have been uncovered. N4‐acetylcytidine (ac4C), a highly conserved RNA modification, has been implicated in human ...

Brugada syndrome (BrS) is a cardiac arrhythmia disorder that causes sudden death in young adults. Rare genetic variants in the SCN5A gene encoding the Na v 1.5 sodium channel and common noncoding ...

Whether cardiovascular dysfunction is associated with preeclampsia in women without fetal growth restriction (FGR) is unclear. Our objective was to investigate associations between third‐trimester ...

In conclusion, while ALLEVIATE‐HF phase 1 provides compelling evidence supporting the safety and potential efficacy of an ICM‐based intervention strategy, several questions remain. The study's ...

To evaluate the efficacy of statin therapy in reducing major adverse cardiovascular event (MACE) risk among patients with breast cancer undergoing breast‐conserving surgery and adjuvant whole breast ...

Among patients diagnosed with high blood pressure (BP), initial dual therapy has been recommended for patients with high pretreatment systolic BP (≥160 mm Hg) since 2003, and first‐line β‐blocker use ...

Acknowledging the limitations inherent to trial‐level network meta‐analyses, the analysis by Ullah et al represents the most comprehensive analysis to date, comparing the different antiplatelet ...

Many specialized cells in adult organs acquire a state of cell cycle arrest and quiescence through unknown mechanisms. Our limited understanding of mammalian cell cycle arrest is derived primarily ...

Historically, the management of carotid artery disease has primarily focused on the degree of stenosis as the main indicator for assessing stroke etiology, risk, and need for intervention. However, ...