Former Dallas Cowboys blasted the team and owner Jerry Jones in a new ESPN feature that dropped ahead of Sunday's matchup ...

On the first play of San Francisco's next possession, rookie running back Isaac Guerendo broke off a 76-yard run to get the 49ers inside the Seahawks' 5-yard line. Two plays later, fullback Kyle ...

is set for 8:15 p.m. ET. San Francisco is a 3.5-point favorite in the latest 49ers vs. Seahawks odds after the line opened at 5.5, while the over/under for total points scored is 49, down from a ...

The San Francisco 49ers entered Thursday Night Football against division rivals the Seattle Seahawks needing a win after a stunning home loss to the Arizona Cardinals last time out. And although there ...

SANTA CLARA, Calif. -- As San Francisco 49ers players walked out of the locker room Friday afternoon, they were greeted by a table full of water bottles, energy bars and other supplements meant to ...

SANTA CLARA — George Kittle and Fred Warner pulled on their 49ers jerseys over their respective shoulder pads Thursday but ended up missing their second straight practice because of injuries.

The San Francisco 49ers have been linked to a blockbuster trade move for Las Vegas Raiders WR Davante Adams. However, the possibility of it happening seems unlikely, according to NBC Sports ...

The San Francisco 49ers haven't been listed as potential suitors ... "Adams is unparalleled when it comes to separating from defenders off the line of scrimmage and running precise routes; he ...

When San Francisco 49ers’ All-Pro running back Christian McCaffrey was scratched from the lineup shortly before the team’s season opener, no one could have predicted what was coming.

Reinforcement is on the way. The San Francisco 49ers are set to receive reinforcement at the defensive line this week. Kalia Davis is having his 21-day practice window open up on Wednesday.

For as much as Christian McCaffrey’s Achilles injury is the talk of the town in 49ers world, there’s little to no clarity on when he’ll actually suit up for San Francisco again.